CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window

CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window

CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window, Published online: 01 August 2018; doi:10.1038/s41586-018-0384-8

A system that targets DNA polymerase activity with CRISPR-guided nickases to provide genetic diversification at user-defined loci enables forward genetic approaches.

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