SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis

SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis

SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis, Published online: 24 April 2019; doi:10.1038/s41586-019-1140-4

The SR-B1 receptor partners with DOCK4 and RAC1 to drive the uptake and transcytosis of LDL in endothelial cells, thereby promoting atherosclerosis in mice.

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