Interleukin-22 protects intestinal stem cells against genotoxic stress

Interleukin-22 protects intestinal stem cells against genotoxic stress

Interleukin-22 protects intestinal stem cells against genotoxic stress, Published online: 30 January 2019; doi:10.1038/s41586-019-0899-7

Sporadic inactivation of the interleukin-22 receptor in the intestinal epithelium of the mouse shows that IL-22 is required for effective activation of the DNA damage response following DNA damage.

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