A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity, Published online: 23 January 2019; doi:10.1038/s41586-019-0878-z

A consortium of 11 bacterial strains from the healthy human gut microbiota can strongly induce interferon-γ-producing CD8 T cells in the intestine, and enhance both resistance to bacterial infection and the therapeutic efficacy of immune checkpoint inhibitors.

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