Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone, Published online: 13 December 2018; doi:10.1038/s41586-018-0790-y

Archived vials of cadaveric human growth hormone contain substantial levels of amyloid-β (Aβ) peptides and can seed Aβ plaques in susceptible mice, suggesting that this material could have transmitted Aβ pathology to humans.

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