Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade, Published online: 17 December 2018; doi:10.1038/s41586-018-0768-9

Deletion of the A-to-I double-stranded RNA-editing enzyme ADAR1 sensitizes tumour cells to immunotherapy.

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