Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast

Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast

Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast, Published online: 01 August 2018; doi:10.1038/s41586-018-0374-x

Yeast chromosomes have been fused to produce viable strains with only two chromosomes that are reproductively isolated from the sixteen-chromosome wild type, but otherwise show high fitness in mitosis and meiosis.

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