A new era of rationally designed antipsychotics

A new era of rationally designed antipsychotics

A new era of rationally designed antipsychotics, Published online: 26 February 2018; doi:10.1038/d41586-018-02328-z

The ideal drugs for treating schizophrenia are postulated to selectively block the D2 dopamine receptor with optimum binding kinetics. The structure of D2 bound to an antipsychotic sheds light on how to design such drugs.

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