CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains, Published online: 03 April 2019; doi:10.1038/s41586-019-1088-4

CD22 inhibits microglial phagocytosis in the ageing brain, and treatment with a CD22-blocking antibody restores microglial homeostasis and cognitive function in ageing mice.

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