Nuclear positioning facilitates amoeboid migration along the path of least resistance

Nuclear positioning facilitates amoeboid migration along the path of least resistance

Nuclear positioning facilitates amoeboid migration along the path of least resistance, Published online: 03 April 2019; doi:10.1038/s41586-019-1087-5

Geometrically defined microenvironments are used to show that leukocytes migrate along chemokine gradients using the nucleus as a mechanical gauge to sample potential paths and identify the path of least resistance.

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